Triethylamine → [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate
반응식
[CH3:1][C:2]1([CH3:9])[O:6][C@H:5]([CH2:7][OH:8])[CH2:4][O:3]1.C(N(CC)CC)C.[CH3:17][S:18](Cl)(=[O:20])=[O:19]>C1COCC1>[CH3:17][S:18]([O:8][CH2:7][C@@H:5]1[CH2:4][O:3][C:2]([CH3:9])([CH3:1])[O:6]1)(=[O:20])=[O:19]참가 물질
5
실험 절차
The (R)-(−)-2,2-dimethyl-1,3-dioxolane-4-methanol (Aldrich, 0.38 mL, 3.1 mmol), triethylamine (0.85 mL, 6.1 mmol), and methanesulfonyl chloride (0.31 mL, 4.1 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
출처 및 근거
- ORD 기록
- ord-e158575da21c4b91b9a0a6b159c58000
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07560481B2
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