Sodium Hydroxide → HCID 28812093, 화합물

HRID 2276424노트

반응식

HRID 2276424 반응식
C[O:2][C:3]([C:5]1[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:17])=[N:7][O:8][C:9]=1[NH2:10])=[O:4].[OH-].[Na+]>CO>[NH2:10][C:9]1[O:8][N:7]=[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:17])[C:5]=1[C:3]([OH:4])=[O:2]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 28473083HCID 28473083, 화합물

생성물 1

HCID 28812093HCID 28812093, 화합물수율 65%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In a similar manner as described in Preparation Example 25, by using methanol (60 mL), methyl-5-amino-3-(2-chlorophenyl)isoxazol-4-carboxylate (6.0 g, 23.75 mmol) and 3% sodium hydroxide aqueous solution (60 mL), a white solid required compound (3.66 g, 15.33 mmol, 65%) was obtained.

후처리

  1. customIn a similar manner as described in Preparation Example 25

출처 및 근거

ORD 기록
ord-9cfb23c244164dc39ba3cf9014bfedcf
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09132126B2

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