Diisopropylethylamine → (R)-2',3'-difluoro-5-(5-methylpyridin-2-yl)-N-(1-morpholinopropan-2-yl)biphenyl-3-carboxamide

반응식

[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][N:16]=2)[CH:12]=[C:11]([C:22](O)=[O:23])[CH:10]=1.Cl.[O:26]1[CH2:31][CH2:30][N:29]([CH2:32][C@H:33]([NH2:35])[CH3:34])[CH2:28][CH2:27]1.F[P-](F)(F)(F)(F)F.C[N+](C)=C(N(C)C)ON1C2N=CC=CC=2N=N1.C(N(CC)C(C)C)(C)C>CN(C)C=O>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][N:16]=2)[CH:12]=[C:11]([C:22]([NH:35][C@H:33]([CH3:34])[CH2:32][N:29]2[CH2:30][CH2:31][O:26][CH2:27][CH2:28]2)=[O:23])[CH:10]=1