3-Hydroxybenzaldehyde → 3-(8-Benzyloxy-3-butylaminoimidazo[1,2-a]pyridin-2-yl)-phenol
반응식
[NH2:1][C:2]1[C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[CH2:16]([N+:20]#[C-:21])[CH2:17][CH2:18][CH3:19].[OH:22][C:23]1[CH:24]=[C:25]([CH:28]=[CH:29][CH:30]=1)[CH:26]=O>Cl(O)(=O)(=O)=O>[CH2:9]([O:8][C:7]1[C:2]2[N:3]([C:21]([NH:20][CH2:16][CH2:17][CH2:18][CH3:19])=[C:26]([C:25]3[CH:24]=[C:23]([OH:22])[CH:30]=[CH:29][CH:28]=3)[N:1]=2)[CH:4]=[CH:5][CH:6]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1참가 물질
5
실험 절차
Compound (8) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-3-benzyloxypyridine solution (0.1 M, DCM), 0.575 ml of n-butyl isocyanide solution (0.2 M, DCM), 0.500 ml of 3-hydroxybenzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).