Thioacetamide → Pyrimidine-2-carbothioamide

HRID 2279646노트

반응식

HRID 2279646 반응식
[C:1]([C:3]1[N:8]=[CH:7][CH:6]=[CH:5][N:4]=1)#[N:2].C(N)(=[S:11])C>Cl>[N:4]1[CH:5]=[CH:6][CH:7]=[N:8][C:3]=1[C:1](=[S:11])[NH2:2]

참가 물질

4

반응물 2

HCID 2723949ThioacetamideHCID 27579792-Cyanopyrimidine

생성물 1

HCID 23273397Pyrimidine-2-carbothioamide

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

반응 조건

온도
90 °C

실험 절차

A mixture of 2-cyanopyrimidine (15 g) and thioacetamide (20 g) in 100 mL of 10% concentrated HCl in Miff is heated with stirring at 90° C. for three hours and cooled. The solid is collected by filtration, washed with water and dried to afford the title compound.

후처리

  1. temperatureis heated
  2. temperaturecooled
  3. filtrationThe solid is collected by filtration
  4. washwashed with water
  5. customdried

출처 및 근거

ORD 기록
ord-ce581895d9db4aed93601a301b61095a
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133204B2

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