C(OC([N:8]1[CH2:12][CH2:11][S:10][C@H:9]1[C:13]([O:15][C@H:16]([C:27]1[CH:32]=[CH:31][C:30]([O:33][CH:34]([F:36])[F:35])=[C:29]([O:37][CH2:38][CH:39]2[CH2:41][CH2:40]2)[CH:28]=1)[CH2:17][C:18]1[C:23]([Cl:24])=[CH:22][N+:21]([O-:25])=[CH:20][C:19]=1[Cl:26])=[O:14])=O)(C)(C)C.Cl>C(OCC)(=O)C>[ClH:24].[Cl:26][C:19]1[CH:20]=[N+:21]([O-:25])[CH:22]=[C:23]([Cl:24])[C:18]=1[CH2:17][C@@H:16]([C:27]1[CH:32]=[CH:31][C:30]([O:33][CH:34]([F:36])[F:35])=[C:29]([O:37][CH2:38][CH:39]2[CH2:41][CH2:40]2)[CH:28]=1)[O:15][C:13]([C@H:9]1[NH:8][CH2:12][CH2:11][S:10]1)=[O:14]4-((S)-2-((S)-3-(tert-butoxycarbonyl)thiazolidine-2-carbonyloxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide (4.22 g, 6.64 mmol) was dissolved in ethyl acetate (10 mL). HCl in ethyl acetate (50 mL, 4.2 M, 210 mmol) was added, and the reaction was stirred at room temperature for 5 minutes. A white precipitate formed, and it was filtered, washed with Ethyl Acetate (2×) and hexane, and dried in a vacuum oven to yield 3,5-dichloro-4-((S)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((S)-thiazolidine-2-carbonyloxy)ethyl)pyridine 1-oxide hydrochloride (3.19 g, 5.6 mmol, 84%)
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