Acetic Anhydride → 2-[3-(Decylcarbamoyl)propyloxy]ethylacetate

HRID 2285948노트

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HRID 2285948 반응식
[CH2:1]([NH:11][C:12](=[O:20])[CH2:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18][OH:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:21](OC(=O)C)(=[O:23])[CH3:22]>C([O-])(=O)C.[Na+].O>[CH2:1]([NH:11][C:12]([CH2:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18][O:19][C:21](=[O:23])[CH3:22])=[O:20])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

5

반응물 2

HCID 7918Acetic AnhydrideHCID 13060240N-decyl-4-(2-hydroxyethoxy)butyramide

생성물 1

HCID 130602412-[3-(Decylcarbamoyl)propyloxy]ethylacetate

시약·촉매·용매 2

HCID 517045Sodium Acetate촉매HCID 962Water용매

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온도
100 °C

실험 절차

In a glass reaction vessel 17.7 grams (0.0616 mole) of N-decyl-4-(2-hydroxyethoxy)butyramide was admixed with 25.3 grams (0.25 mole) of acetic anhydride in the presence of 4 grams sodium acetate catalyst. This mixture was heated to 100° C. on a steam bath until a reaction was completed within a period of 3 hours. The mixture was then drowned in water, salted out and phase separated. The upper liquid phase was dried to 17.8 grams of liquid product having a refractive index ηd25 =1.4586 and an IR of 6.09 mu.

후처리

  1. customphase separated
  2. dry with materialThe upper liquid phase was dried to 17.8 grams of liquid product

출처 및 근거

ORD 기록
ord-6581d561927a4a3ea036d27eeef88024
출처 데이터셋
uspto-grants-1982_04
특허 번호
US04325973

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