2,2,2-Trifluoroethanol → 2,2,2-Trifluoroethyl benzenesulfonate

HRID 2286420

반응식

HRID 2286420 반응식
[OH-].[Na+].[F:3][C:4]([F:8])([F:7])[CH2:5][OH:6].[S:9](Cl)([OH:12])(=O)=[O:10].[CH:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>O>[F:3][C:4]([F:8])([F:7])[CH2:5][O:6][S:9]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:12])=[O:10]

참가 물질

5

반응물 3

HCID 64092,2,2-TrifluoroethanolHCID 14798Sodium HydroxideHCID 22564087Benzene sulphochloride

생성물 1

HCID 2963412,2,2-Trifluoroethyl benzenesulfonate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

4.4 Moles of a 30% aqueous solution of sodium hydroxide were dissolved in 4 moles of 2,2,2-trifluoroethanol with cooling to maintain the temperature of the reaction mixture between 50° and 55° C. The solution was added at once with stirring at the same temperature to a mixture of 4.2 moles of benzene sulphochloride and 1 liter of water, which had also been brought at 50°-55° C. After 10 min of stirring the oil layer was decanted and washed with 1 liter of water. The oil was filtered through paper to remove water drops.

후처리

  1. temperaturewith cooling
  2. temperatureto maintain the temperature of the reaction mixture between 50° and 55° C
  3. additionThe solution was added at once
  4. customhad also been brought at 50°-55° C
  5. customwas decanted
  6. washwashed with 1 liter of water
  7. filtrationThe oil was filtered through paper
  8. customto remove water drops

출처 및 근거

ORD 기록
ord-e29555b98b224cb2af7122d497fe72e7
출처 데이터셋
uspto-grants-1981_05
특허 번호
US04266014

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