Dimethylformamide → 5-Benzyloxy-3-methoxyxanthone

HRID 2286907노트

반응식

HRID 2286907 반응식
[CH2:1]([O:8][C:9]1[CH:22]=[CH:21][CH:20]=[C:19]2[C:10]=1[O:11][C:12]1[CH:13]=[C:14](Cl)[CH:15]=[CH:16][C:17]=1[C:18]2=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Na+].CN(C)[CH:29]=[O:30]>O>[CH2:1]([O:8][C:9]1[CH:22]=[CH:21][CH:20]=[C:19]2[C:10]=1[O:11][C:12]1[CH:13]=[C:14]([O:30][CH3:29])[CH:15]=[CH:16][C:17]=1[C:18]2=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 6228DimethylformamideHCID 24758Sodium hydrideHCID 234605165-Benzyloxy-3-chloroxanthone

생성물 1

HCID 234605085-Benzyloxy-3-methoxyxanthone

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 5-benzyloxy-3-chloroxanthone (8.5 g.), sodium hydride (3 g.), methaol (20 ml.) and dimethylformamide (100 ml.) is stirred at room temperature for 24 hours. The mixture is poured into water and the precipitate is filtered. The residue is recrystallised from isopropanol to give 5-benzyloxy-3-methoxyxanthone, m.p. 158° C.

후처리

  1. filtrationthe precipitate is filtered
  2. customThe residue is recrystallised from isopropanol

출처 및 근거

ORD 기록
ord-794c8866182b47af8f365a9222060da1
출처 데이터셋
uspto-grants-1981_05
특허 번호
US04268514

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