Hydroxyamine hydrochloride → HCID 12876704, 화합물

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[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH:10]([C:15](=O)[CH2:16][CH3:17])[C:11](=[O:14])[CH2:12][CH3:13])=[CH:5][CH:4]=1.Cl.[NH2:20]O>N1C=CC=CC=1>[CH2:16]([C:15]1[C:10]([CH2:9][C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[C:11]([CH2:12][CH3:13])[O:14][N:20]=1)[CH3:17]

참가 물질

실험 절차

3,5-Diethyl-4-[(4-methoxyphenyl)methyl]isoxazole [I; Ar is 4-CH3OC6H4, Y is CH2, R is C2H5 ] was prepared from 41.1 g. of 4-(4-methoxyphenylmethyl)-3,5-heptanedione and 12.0 g. of hydroxylamine hydrochloride in 100 ml. of pyridine according to the procedure of Example 2, part (b), and was obtained in the form of a colorless oil, b.p. 145°-146° C. (0.1 mm.); MIC=25 μg/ml (herpes 2).