Iodoethane → HCID 178477485, 화합물

HRID 2288921노트

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HRID 2288921 반응식
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15]([NH2:17])=[S:16])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:18][CH2:19][CH3:20]>CC(C)=O>[IH:18].[CH2:19]([S:16][C:15](=[NH:17])[NH:14][C:11]1[CH:12]=[CH:13][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH3:20]

참가 물질

4

반응물 2

HCID 6340IodoethaneHCID 27603494-Phenoxyphenylthiourea

생성물 1

HCID 178477485HCID 178477485, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To a stirred solution of 1-(4-phenoxyphenyl)-2-thiourea (2.00 g, 8.19 mmol) in acetone (20 ml) was added iodoethane (7.61 g, 48.7 mmol). The mixture was heated to reflux for three hours, cooled to room temperature and concentrated at reduced pressure. The resulting viscous oil was crystallized from acetone-pentane to afford S-ethyl-N-(4-phenoxyphenyl)isothiourea hydroiodide as a beige solid. Mp=140-143° C.

후처리

  1. temperatureThe mixture was heated
  2. temperatureto reflux for three hours
  3. concentrationconcentrated at reduced pressure
  4. customThe resulting viscous oil was crystallized from acetone-pentane

출처 및 근거

ORD 기록
ord-7a6304c653db46079f31e2c05d58d57f
출처 데이터셋
uspto-grants-2000_07
특허 번호
US06090846

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