Methanol → HCID 136332165, 화합물
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[C:9](=[N:11][OH:12])[CH3:10])=[CH:4][CH:3]=1.[NH2:14][NH:15][C:16]([NH2:18])=[S:17].CO>C(O)(=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[N:14][NH:15][C:16]([NH2:18])=[S:17])[C:9](=[N:11][OH:12])[CH3:10])=[CH:4][CH:3]=1참가 물질
5
실험 절차
A mixture of 4'-chloro-2-hydroxyiminopropiophenone (252.3 g), thiosemicarbazide (151.3 g), methanol (650 ml) water (300 ml), and acetic acid (9 ml) was refluxed for 31 hours with stirring. After cooling, the resulting precipitates were collected by filtration, washed successively with methanol, water and methanol, and then dried to give 4'-chloro-2-hydroxyiminopropiophenone thiosemicarbazone (298.88 g).
후처리
- temperaturewas refluxed for 31 hours
- temperatureAfter cooling
- customthe resulting precipitates
- filtrationwere collected by filtration
- washwashed successively with methanol, water and methanol
- customdried
출처 및 근거
- ORD 기록
- ord-d460d2d077154021a548584d4355b394
- 출처 데이터셋
- uspto-grants-1986_10
- 특허 번호
- US04616014
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