Ethanesulfonyl chloride → Ethanesulfonic acid;7-hydroxy-3,4-dimethylchromen-2-one

HRID 2290764노트

반응식

HRID 2290764 반응식
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:14])=[C:7]([CH3:13])[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[CH2:15]([S:17](Cl)(=[O:19])=[O:18])[CH3:16]>O.[OH-].[Na+]>[CH2:15]([S:17]([OH:19])(=[O:1])=[O:18])[CH3:16].[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:14])=[C:7]([CH3:13])[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1

참가 물질

5

반응물 2

HCID 11667Ethanesulfonyl chlorideHCID 54129907-hydroxy-3,4-dimethyl-2H-chromen-2-one

생성물 1

HCID 86741079Ethanesulfonic acid;7-hydroxy-3,4-dimethylchromen-2-one

시약·촉매·용매 2

HCID 962Water용매HCID 14798Sodium Hydroxide용매

실험 절차

5.0 g of 7-hydroxy-3,4-dimethylcoumarin were dissolved in 20 ml of H2O/1.1 g of NaOH at room temperature, while stirring, and 3.4 g of ethanesulfonyl chloride were added. The mixture was stirred overnight, and the precipitate was filtered off under suction and recrystallized from ethanol.

후처리

  1. stirringThe mixture was stirred overnight
  2. filtrationthe precipitate was filtered off under suction
  3. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-6ef9b4ad9f104ef58760f70b6ee8b4cf
출처 데이터셋
uspto-grants-1986_10
특허 번호
US04618622

반응 노트

불러오는 중…