Hydrochloric Acid → Diltiazem

HRID 2291252노트

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Cl.Cl.[C:3]([O:6][CH:7]1[C:13](=[O:14])[N:12]([CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])[C:11]2[CH:20]=[CH:21][CH:22]=[CH:23][C:10]=2[S:9][CH:8]1[C:24]1[CH:29]=[CH:28][C:27]([O:30][CH3:31])=[CH:26][CH:25]=1)(=[O:5])[CH3:4]>>[CH3:4][C:3]([O:6][C@H:7]1[C:13](=[O:14])[N:12]([CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])[C:11]2[CH:20]=[CH:21][CH:22]=[CH:23][C:10]=2[S:9][C@H:8]1[C:24]1[CH:29]=[CH:28][C:27]([O:30][CH3:31])=[CH:26][CH:25]=1)=[O:5]

참가 물질

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HCID 313Hydrochloric Acid

HCID 2144641,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, hydrochloride (1:1)

생성물 1

HCID 39186Diltiazem

실험 절차

HCl: 3-acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride

출처 및 근거

ORD 기록: ord-08a9a6154bcd484089b5fe97fcff2854
출처 데이터셋: uspto-grants-1989_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04795643

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