Diazomethane → 1-Diazo-2-(4-isopropyl-1-methylcyclohexyl)-2-ethanone
반응식
[CH:1]([CH:4]1[CH2:9][CH2:8][C:7]([CH3:13])([C:10](Cl)=[O:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2].[N+:14](=[CH2:16])=[N-:15].N(NC(N)=O)=O>CCOCC>[N+:14](=[CH:16][C:10]([C:7]1([CH3:13])[CH2:8][CH2:9][CH:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6]1)=[O:11])=[N-:15]참가 물질
5
실험 절차
Subsequently at room temperature, 5.0 g of the 4-isopropyl-1-methylcyclohexylcarbonyl chloride was added dropwise to 150 ml of an ether solution of diazomethane prepared from 15 g of nitrosourea, and the mixture was stirred at room temperature for about 2 hours. The solvent was distilled off from the reaction mixture in a vacuum, quantitatively giving pale yellow oily 1-diazo-2-(4-isopropyl-1-methylcyclohexyl)-2-ethanone (cis:trans=1:1).
후처리
- distillationThe solvent was distilled off from the reaction mixture in a vacuum
출처 및 근거
- ORD 기록
- ord-e98eb2d8bb8a42cbbbdc3f7f1a64b4f5
- 출처 데이터셋
- uspto-grants-1989_01
- 특허 번호
- US04797502
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