Acetic Anhydride → HCID 54540459, 화합물
반응식
C(N(CC)CC)C.[CH2:8]([C:10](=[CH:15][CH:16]([CH3:18])[CH3:17])[CH:11]=[CH:12][CH2:13][NH2:14])[CH3:9].[C:19](OC(=O)C)(=[O:21])[CH3:20]>ClCCl>[C:19]([NH:14][CH2:13][CH:12]=[CH:11][C:10]([CH2:8][CH3:9])=[CH:15][CH:16]([CH3:17])[CH3:18])(=[O:21])[CH3:20]참가 물질
5
실험 절차
To a solution of triethylamine (2.22 g) and 4-ethyl-6-methyl-2,4-heptadiene-1-ylamine (3.07 g) in dichloromethane (50 ml) at 0° C. was added dropwise acetic anhydride (4.08 g). After one hour, the reaction mixture was washed with water and brine, dried over anhydrous magnesium sulfate, and evaporated in vacuo. The residue was chromatographed on silica gel (10% methanol-chloroform) to give 1-acetylamino-4-ethyl-6-methyl-2,4-heptadiene (3.86 g) as an oil.
후처리
- washthe reaction mixture was washed with water and brine
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated in vacuo
- customThe residue was chromatographed on silica gel (10% methanol-chloroform)
출처 및 근거
- ORD 기록
- ord-934ae8e89b2542d58dec4399503914b8
- 출처 데이터셋
- uspto-grants-1997_11
- 특허 번호
- US05691366
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