Acetic Anhydride → (E,E)-1-acetoxy-4-ethyl-2,4-heptadiene
반응식
[CH2:1](/[C:3](=[CH:8]\[CH2:9][CH3:10])/[CH:4]=[CH:5]/[CH2:6][OH:7])[CH3:2].[C:11](OC(=O)C)(=[O:13])[CH3:12]>N1C=CC=CC=1>[C:11]([O:7][CH2:6]/[CH:5]=[CH:4]/[C:3](/[CH2:1][CH3:2])=[CH:8]/[CH2:9][CH3:10])(=[O:13])[CH3:12]참가 물질
4
실험 절차
To a solution of (E,E)-4-ethyl-2,4-heptadien-1-ol (10.1 g) in pyridine (29 g) at 0° C. was added dropwise acetic anhydride (22.2 g). After two hours at room temperature, the reaction mixture was evaporated in vacuo. The residue was diluted with ethyl acetate, washed with 0.5N hydrochloric acid and brine, dried over anhydrous magnesium sulfate, and evaporated in vacuo. The residue was chromatographed on silica gel (5% ethyl acetate in hexane) to give (E,E)-1-acetoxy-4-ethyl-2,4-heptadiene (9.75 g) as an oil.
후처리
- customthe reaction mixture was evaporated in vacuo
- additionThe residue was diluted with ethyl acetate
- washwashed with 0.5N hydrochloric acid and brine
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated in vacuo
- customThe residue was chromatographed on silica gel (5% ethyl acetate in hexane)
출처 및 근거
- ORD 기록
- ord-442d74d91b0346fcb231f3e075946fd2
- 출처 데이터셋
- uspto-grants-1997_11
- 특허 번호
- US05691366
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