Tetrahydrofuran → (S)-2-Amino-1-{4-[(4-benzyloxy-phenyl)-(3-methyl-but-2-enyl)-amino]-piperidin-1-yl}-4-methyl-pentan-1-one

반응식

C(O[C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=[O:7])(C)(C)C.C([N:32]([CH2:36][CH3:37])C(C)C)(C)C.Br[CH2:39][CH:40]=[C:41]([CH3:43])[CH3:42].[CH2:44]1[CH2:48]OC[CH2:45]1>>[NH2:32][C@@H:36]([CH2:37][CH:44]([CH3:48])[CH3:45])[C:6]([N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:17][CH:16]=2)[CH2:39][CH:40]=[C:41]([CH3:43])[CH3:42])[CH2:12][CH2:13]1)=[O:7]