Ammonia → Urea, N,N'-bis(phenylmethyl)-

HRID 2300036

반응식

HRID 2300036 반응식
[NH2:1][C:2]([NH2:4])=[O:3].[CH2:5](N)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.N>>[CH2:5]([NH:1][C:2]([NH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:3])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 1176UreaHCID 7504Benzylamine

생성물 1

HCID 72889Urea, N,N'-bis(phenylmethyl)-수율 599.4%

실험 절차

Heated was a mixture of urea 5.84 g (9.72 mmol) and benzylamine 25.0 g (23.3 mmol, 2.4 equivalents) at 150° C.-155° C. for 5 hours attaching with an air cooler. During the heating, observed was the ammonia gas evolution from colorless liquid reaction mixture. By cooling, it turned solidified at around room temperature. Purified was the reaction product by recrystallization from ethanol-benzene (1:1 mixture) to give N,N′-dibenzylurea 14.0 g as white fine needles (59.9% yield).

후처리

  1. temperatureHeated
  2. customfrom colorless liquid reaction mixture
  3. temperatureBy cooling
  4. customturned solidified at around room temperature
  5. customPurified
  6. customby recrystallization from ethanol-benzene (1:1 mixture)

출처 및 근거

ORD 기록
ord-2828b789b1a44f70be3e7ce81ebdc615
출처 데이터셋
uspto-grants-2002_12
특허 번호
US06498164B1

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