2-Chloropropionic acid → N-(3,5-difluorophenyl)alanine

HRID 23013

반응식

HRID 23013 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([F:9])[CH:8]=1)[NH2:5].Cl[CH:11]([CH3:15])[C:12]([OH:14])=[O:13]>>[F:1][C:2]1[CH:3]=[C:4]([NH:5][C@H:11]([C:12]([OH:14])=[O:13])[CH3:15])[CH:6]=[C:7]([F:9])[CH:8]=1

참가 물질

3

반응물 2

HCID 117342-Chloropropionic acidHCID 965953,5-Difluoroaniline

생성물 1

HCID 53936901N-(3,5-difluorophenyl)alanine

실험 절차

Using the procedure set forth in U.S. Pat. No. 3,598,859 and Example Q above, N-(3,5-difluorophenyl)alanine was prepared using 3,5-difluoroaniline (Aldrich) and 2-chloropropionic acid (Aldrich).

출처 및 근거

ORD 기록
ord-4603fdb65ae248febb22cc11c07a9866
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06849650B2

연결된 노트

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