4-Iodophenol → HCID 57762623, 화합물

HRID 230297

반응식

HRID 230297 반응식
[I:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[C:10]1[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[C:12]([O:18][CH3:19])[N:11]=1.[H-].[Na+]>>[I:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:10]2[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[C:12]([O:18][CH3:19])[N:11]=2)=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 108944-IodophenolHCID 24758Sodium hydrideHCID 51523232-Chloro-4,6-dimethoxypyrimidine

생성물 1

HCID 57762623HCID 57762623, 화합물수율 88.7%

실험 절차

In the same manner as in Reference Example 8, 4-iodophenol (223 mg) and 2-chloro-4,6-dimethoxypyrimidine (192 mg) were reacted by using sodium hydride to obtain 2-(4-iodophenoxy)-4,6-dimethoxypyrimidine (322 mg).

출처 및 근거

ORD 기록
ord-f60850634e7e4ad29d4265ccdec02b92
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07566724B2

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