Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Mesitylenesulfonyl chloride → 2,4,6-Trimethyl-N-[2-[(phenylsulfonyl)amino]4-(1-piperazinyl)phenyl]benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Mesitylenesulfonyl chloride | HCID 13046 | — |
| 반응물 | N-(2-amino-5-(4-boc-1-piperazinyl)-phenyl)-benzenesulfonamide | HCID 22272479 | — |
| 생성물 | 2,4,6-Trimethyl-N-[2-[(phenylsulfonyl)amino]4-(1-piperazinyl)phenyl]benzenesulfonamide | HCID 10207921 | — |
반응 단계
2,4,6-Trimethyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and 2-mesitylenesulfonylchloride (52 mg, 0.239 mmol) according to general method 3 to give 50 mg of a purple solid. MS (posES-FIA) m/z=Found: 515.3; Calcd 515.17; 1H-NMR δ 7.74 (d, 2H); 7.63-7.46 (m, 3H), 6.92 (s, 2H), 6.74-6.55 (m, 3H), 3.27-3.20 (m, 8H), 2.35 (s, 6H), 2.25 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07566715B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-82c1a1bc1c5a42be8c3bfef05ceb9658 |
| 출처 메모 | uspto-grants-2009_07 |