Ethyl isocyanate → HCID 15871432, 화합물

HRID 23058

반응식

HRID 23058 반응식
[CH2:1]([N:3]=[C:4]=[O:5])[CH3:2].[N:6]1([CH2:11][CH2:12][CH2:13][NH2:14])[CH2:10][CH2:9][CH2:8][CH2:7]1>C(Cl)(Cl)Cl>[CH2:1]([NH:3][C:4]([NH:14][CH2:13][CH2:12][CH2:11][N:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2]

참가 물질

4

반응물 2

HCID 8022Ethyl isocyanateHCID 316701-Pyrrolidinepropanamine

생성물 1

HCID 15871432HCID 15871432, 화합물수율 96.4%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

To a solution of 27.7 g (0.39 mol) ethyl isocyanate in 250 mL chloroform was added 50 g (0.39 mol) 3-(1-pyrrolidinyl)propylamine dropwise with cooling. Once the addition was complete, the cooling bath was removed and the reaction mixture stirred at room temperature for 4 hours. The reaction mixture was then concentrated under reduced pressure to give 74.5 g (96.4%) of the desired urea as a clear oil.

후처리

  1. temperaturewith cooling
  2. additionOnce the addition
  3. customthe cooling bath was removed
  4. concentrationThe reaction mixture was then concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-592ba205f2284c8a92152d6f0b997396
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06849650B2

연결된 노트

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