4,4'-Dihydroxybiphenyl → 4'-(2-Methylbutoxy)(1,1'-biphenyl)-4-ol

HRID 231005

반응식

HRID 231005 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17]Br.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

참가 물질

5

반응물 3

HCID 71124,4'-DihydroxybiphenylHCID 11430Potassium CarbonateHCID 252541-Bromo-2-methylbutane

생성물 1

HCID 140938154'-(2-Methylbutoxy)(1,1'-biphenyl)-4-ol수율 58%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 0.20 mole(37.2 g) of 4,4'-dihydroxybiphenyl, 0.10 mole(15.1 g) of the above 2-methyl-1-bromobutane, and 0.60 mole(33.7 g) of potassium carbonate in 300 ml of ethanol was refluxed for 16 hours. After the reaction, the reaction solution was filtered and concentrated, then purified by column chromatography to obtain 4.9 g of 4'-(2-methylbutoxy)-4-hydroxybiphenyl. (yield: 58%)

후처리

  1. customAfter the reaction
  2. filtrationthe reaction solution was filtered
  3. concentrationconcentrated
  4. custompurified by column chromatography

출처 및 근거

ORD 기록
ord-7579d4eec5224c2fa2bdb88004109b17
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04844835

연결된 노트

불러오는 중…