Hydrochloric Acid → 2-Amino-5-methoxybenzene-1-thiol

HRID 231054

반응식

HRID 231054 반응식
[OH-].[K+].NC1[S:5][C:6]2[CH:12]=[C:11]([O:13][CH3:14])[CH:10]=[CH:9][C:7]=2[N:8]=1.Cl>C(O)(=O)C>[NH2:8][C:7]1[CH:9]=[CH:10][C:11]([O:13][CH3:14])=[CH:12][C:6]=1[SH:5]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 156302-Amino-6-methoxybenzothiazole

생성물 1

HCID 2355092-Amino-5-methoxybenzene-1-thiol

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

To a stirred solution of 8N potassium hydroxide (1.3 1) was added 2-amino-6-methoxybenzothiazole (750 g) and the mixture was refluxed overnight. The resulting solution was neutralized by the addition of conc. HCl to pH 8.0, then acetic acid to pH 6.0. The precipitate which formed was filtered and washed with water to afford the title compound which was used immediately in Step 3.

후처리

  1. temperaturethe mixture was refluxed overnight
  2. customThe precipitate which formed
  3. filtrationwas filtered
  4. washwashed with water

출처 및 근거

ORD 기록
ord-2cd057767225428ea19ca870db47e56a
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04845083

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