Methyl Methanesulfonate → 2-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium mesylate

HRID 231263

반응식

HRID 231263 반응식
[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N:10]([CH3:12])[CH3:11])(=[O:7])=[O:6].[CH3:33][S:34]([O:37]C)(=[O:36])=[O:35]>C(Cl)(Cl)Cl>[S:34]([O-:37])(=[O:36])(=[O:35])[CH3:33].[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N+:10]([CH3:33])([CH3:12])[CH3:11])(=[O:6])=[O:7]

참가 물질

4

반응물 2

HCID 4156Methyl MethanesulfonateHCID 144982652-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine

생성물 1

HCID 144982462-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium mesylate수율 70.6%

시약·촉매·용매 1

HCID 6212Chloroform용매

반응 조건

온도
70 °C

실험 절차

In 10 ml of chloroform are dissolved 0.48 g of 2-[(2-methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine and 1 g of methyl methanesulfonate and the solution is stirred at 70° C. for 5 hours. Then the reaction mixture is concentrated under reduced pressure and the residue is crystallized from chloroform and ether to give 417 mg of the captioned compound.

후처리

  1. concentrationThen the reaction mixture is concentrated under reduced pressure
  2. customthe residue is crystallized from chloroform and ether

출처 및 근거

ORD 기록
ord-1c6f273932834c8c827785532613c3dc
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04845219

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