Sodium hydroxide ethanol → Sodium butyl glycidyl phosphate

HRID 231284

반응식

HRID 231284 반응식
[P:1]([O-:14])([O:8][CH2:9][CH:10]([OH:13])[CH2:11]Cl)([O:3][CH2:4][CH2:5][CH2:6][CH3:7])=[O:2].[Na+:15].C(O)C.[OH-].[Na+]>C(O)C>[P:1]([O-:14])([O:8][CH2:9][CH:10]1[O:13][CH2:11]1)([O:3][CH2:4][CH2:5][CH2:6][CH3:7])=[O:2].[Na+:15]

참가 물질

4

반응물 2

HCID 23692425Sodium hydroxide ethanolHCID 86743212HCID 86743212, 화합물

생성물 1

HCID 23698436Sodium butyl glycidyl phosphate수율 100%

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
70 °C

실험 절차

50 g (0.19 mol) of sodium butyl 2-hydroxy-3chloropropyl phosphate was charged into a reactor, to which 1000 ml of ethanol was added, followed by agitation and heating to 70° C. to obtain a uniform mixture. Thereafter, the reaction system was cooled down to room temperature, to which was gradually added 88.6 g (0.19 mol) of a 0.0021 mol/g sodium hydroxide ethanol solution, followed by agitation for 3 hours while keeping the temperature. The HPLC analysis revealed the disappearance of a peak of the starting material with a peak for the resultant new product appearing. The resultant NaCl precipitate was removed by filtration and the ethanol was distilled off under reduced pressure to obtain 43 g (yield: 100%) of sodium butyl glycidyl phosphate.

후처리

  1. additionwas added
  2. customto obtain a uniform mixture
  3. temperatureThereafter, the reaction system was cooled down to room temperature, to which
  4. customThe resultant NaCl precipitate was removed by filtration
  5. distillationthe ethanol was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-e17e630651bc4823b01a22b74fce5162
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04845239

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