Barium Sulfate → 2,4-Difluorobenzaldehyde
반응식
S([O-])([O-])(=O)=O.[Ba+2].[F:7][C:8]1[CH:16]=[C:15]([F:17])[CH:14]=[CH:13][C:9]=1[C:10](Cl)=[O:11]>[Pd].C1C2C(CCCC2)CCC1>[F:7][C:8]1[CH:16]=[C:15]([F:17])[CH:14]=[CH:13][C:9]=1[CH:10]=[O:11]참가 물질
5
반응 조건
- 온도
- 130 °C
실험 절차
30 ml (27 g) of decahydronaphthalene and 0.5 g (2.3×10-4 ml) of a catalyst of 5% palladium on a barium sulfate support were added to the flask containing the 2,4-difluorobenzoylchloride. The reaction was purged with H2 for 0.25 hour, then the temperature was raised to 130° C. Hydrogen was dispersed through the system for 6 hours. The product 2,4-difluorobenzaldehyde was isolated as a colorless liquid. Yield 9.8 g (82%).
후처리
- customThe reaction was purged with H2 for 0.25 hour
- additionHydrogen was dispersed through the system for 6 hours
출처 및 근거
- ORD 기록
- ord-75dc8a895d0348e8b51de7c7dc829a70
- 출처 데이터셋
- uspto-grants-1989_07
- 특허 번호
- US04847442
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