Isopropanol → HCID 20032021, 화합물

반응식

Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([N:8]2[CH:12]=[CH:11][CH:10]=[N:9]2)[CH:3]=1.[Na].[CH:14]([OH:17])([CH3:16])[CH3:15]>>[CH:14]([O:17][C:2]1[N:7]=[CH:6][N:5]=[C:4]([N:8]2[CH:12]=[CH:11][CH:10]=[N:9]2)[CH:3]=1)([CH3:16])[CH3:15]

참가 물질

반응물 3

HCID 3776Isopropanol

HCID 5360545Sodium

HCID 106312394-Chloro-6-(1H-pyrazol-1-yl)pyrimidine

생성물 1

HCID 20032021HCID 20032021, 화합물

실험 절차

Following the procedure of Example 15, 180 mg of 6-chloro-4-(1-pyrazolyl)pyrimidine was reacted with 23 mg of sodium metal and 3 ml of anhydrous isopropylalcohol to yield 127 mg of an oily substance, 6-isopropoxy-4-(1-pyrazolyl)pyrimidine,

출처 및 근거

ORD 기록: ord-1296cb7ec74a4192a79345e6c0e218ca
출처 데이터셋: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04849424

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