3-Octanone → N-[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl]octan-3-amine
반응식
[N:1]1([C:6]2[CH:15]=[CH:14][C:9]([O:10][CH2:11][CH2:12][NH2:13])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[CH3:16][CH2:17][C:18](=O)[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].C([BH3-])#N.[Na+]>CO>[N:1]1([C:6]2[CH:15]=[CH:14][C:9]([O:10][CH2:11][CH2:12][NH:13][CH:18]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:17][CH3:16])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1참가 물질
5
실험 절차
In a manner similar to Preparation 8, react 2-[4-(1H-imidazol-1-yl)phenoxy]ethanamine with 3-octanone and sodium cyanoborohydride in methanol to obtain the title compound.
후처리
- customIn a manner similar to Preparation 8
출처 및 근거
- ORD 기록
- ord-6e329288a7b94df3b4da921186b88640
- 출처 데이터셋
- uspto-grants-1989_07
- 특허 번호
- US04851526
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