3-Octanone → N-[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl]octan-3-amine

HRID 232324

반응식

HRID 232324 반응식
[N:1]1([C:6]2[CH:15]=[CH:14][C:9]([O:10][CH2:11][CH2:12][NH2:13])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[CH3:16][CH2:17][C:18](=O)[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].C([BH3-])#N.[Na+]>CO>[N:1]1([C:6]2[CH:15]=[CH:14][C:9]([O:10][CH2:11][CH2:12][NH:13][CH:18]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:17][CH3:16])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

5

반응물 3

HCID 2467283-OctanoneHCID 5003444Sodium cyanoborohydrideHCID 145556572-[4-(Imidazol-1-yl)phenoxy]ethylamine

생성물 1

HCID 20031309N-[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl]octan-3-amine

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In a manner similar to Preparation 8, react 2-[4-(1H-imidazol-1-yl)phenoxy]ethanamine with 3-octanone and sodium cyanoborohydride in methanol to obtain the title compound.

후처리

  1. customIn a manner similar to Preparation 8

출처 및 근거

ORD 기록
ord-6e329288a7b94df3b4da921186b88640
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04851526

연결된 노트

불러오는 중…