Sodium borohydride → HCID 20031377, 화합물

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:16][CH:15]([C:17]([C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH:29]=[CH:28][N:27]=[CH:26]4)=[CH:21][CH:20]=3)=[O:18])[CH2:14]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[BH4-].[Na+]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:14][CH:15]([CH:17]([C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH:29]=[CH:28][N:27]=[CH:26]4)=[CH:21][CH:20]=3)[OH:18])[CH2:16]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

참가 물질

반응물 2

HCID 4311764Sodium borohydride

HCID 14555636HCID 14555636, 화합물

생성물 1

HCID 20031377HCID 20031377, 화합물

실험 절차

In a manner similar to Example 27, react [1-[2-(3,4-dimethoxyphenyl)ethyl]azetidin-3-yl][4-(1H-imidazol-yl)phenyl]methanone with sodium borohydride to obtain the title compound.

출처 및 근거

ORD 기록: ord-baf9598094c2455989851b07e98a22ae
출처 데이터셋: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04851526

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