Sodium borohydride → HCID 14555639, 화합물

반응식

[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[BH4-].[Na+]>>[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][CH:12]([C:14]2[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:16][CH:15]=2)[OH:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 4311764Sodium borohydride

HCID 20031304HCID 20031304, 화합물

생성물 1

HCID 14555639HCID 14555639, 화합물

실험 절차

In a manner similar to Example 27, react 5-[(cyclopentylmethyl)(2-propenyl)amino]-1-[4-(1H-imidazol-1-yl)-phenyl]hexan-1-one with sodium borohydride to obtain the title compound.

출처 및 근거

ORD 기록: ord-d717629a8c2d4e9982dad3399e9753a4
출처 데이터셋: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04851526

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