Nitric Acid → 2,6-Dichloro-3-nitrotoluene

HRID 232641

반응식

HRID 232641 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9].[N+:10]([O-])([OH:12])=[O:11]>>[Cl:1][C:2]1[C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9]

참가 물질

3

반응물 2

HCID 944Nitric AcidHCID 83682,6-Dichlorotoluene

생성물 1

HCID 971552,6-Dichloro-3-nitrotoluene

실험 절차

To 2,6-dichlorotoluene (200 g) is added dropwise fuming nitric acid (d=1.52, 206 ml) at 25° to 30° C. After stirring for 30 minutes at room temperature, the mixture is poured into ice-water, extracted with diethyl ether, and the extract is washed with an aqueous sodium hydrogen carbonate solution and then dried. The solvent is distilled off under reduced pressure to give 2,6-dichloro-3-nitrotoluene as yellow crystals (253.2 g).

후처리

  1. extractionextracted with diethyl ether
  2. washthe extract is washed with an aqueous sodium hydrogen carbonate solution
  3. customdried
  4. distillationThe solvent is distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-ce6e3c6086de4446ad76aa28c6e59e4f
출처 데이터셋
uspto-grants-1997_01
특허 번호
US05591744

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