Acetonitrile → 6-Bromo-4-(tetrahydro-2H-pyran-4-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one

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[Br:1][c:2]1[c:3]([NH:9][C:10]([CH2:11][I:12])=[O:13])[n:4][cH:5][c:6]([Br:8])[n:7]1.[CH3:30][C:31]#[N:32].[CH:14]([N:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][CH3:20])([CH3:21])[CH3:22].[O:23]1[CH2:24][CH2:25][CH:26]([NH2:29])[CH2:27][CH2:28]1>>[c:2]12[c:3]([n:4][cH:5][c:6]([Br:8])[n:7]1)[NH:9][C:10](=[O:13])[CH2:11][N:29]2[CH:26]1[CH2:25][CH2:24][O:23][CH2:28][CH2:27]1