Hydrochloric Acid → 2-{[6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid ethyl ester

HRID 2327272

반응식

HRID 2327272 반응식
[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH2:6][CH3:7])([CH2:8][CH3:9])[NH:10][C:11](=[O:12])[c:13]1[n:14][c:15]([O:20][CH2:21][CH:22]2[CH2:23][CH2:24]2)[c:16]([Br:19])[cH:17][cH:18]1)=[O:25].[ClH:26].[F:27][C:28]1([F:32])[CH2:29][NH:30][CH2:31]1>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH2:6][CH3:7])([CH2:8][CH3:9])[NH:10][C:11](=[O:12])[c:13]1[n:14][c:15]([O:20][CH2:21][CH:22]2[CH2:23][CH2:24]2)[c:16]([N:30]2[CH2:29][C:28]([F:27])([F:32])[CH2:31]2)[cH:17][cH:18]1)=[O:25]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 27582483,3-DifluoroazetidineHCID 710872802-[(5-Bromo-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid ethyl ester

생성물 1

HCID 710874672-{[6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid ethyl ester

출처 및 근거

ORD 기록
ord-6c913b39550e4dacac71673844e33523
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

연결된 노트

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