Allyl bromide → HCID 67684035, 화합물

HRID 232779

반응식

HRID 232779 반응식
[O:1]1[C:5]2([CH2:10][CH2:9][N:8]([C@H:11]3[CH2:28][C@@:27]4([CH3:29])[C@@H:14]([CH2:15][CH2:16][C@@H:17]5[C@@H:26]4[CH2:25][CH2:24][C@@:22]4([CH3:23])[C@H:18]5[CH2:19][C@H:20]([N:31]5[CH2:35][CH2:34][CH2:33][CH2:32]5)[C@@H:21]4[OH:30])[CH2:13][C@@H:12]3[OH:36])[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.[CH2:37]([Br:40])[CH:38]=[CH2:39]>>[Br-:40].[OH:36][C@@H:12]1[C@@H:11]([N:8]2[CH2:7][CH2:6][C:5]3([O:4][CH2:3][CH2:2][O:1]3)[CH2:10][CH2:9]2)[CH2:28][C@@:27]2([CH3:29])[C@@H:14]([CH2:15][CH2:16][C@@H:17]3[C@@H:26]2[CH2:25][CH2:24][C@@:22]2([CH3:23])[C@H:18]3[CH2:19][C@H:20]([N+:31]3([CH2:39][CH:38]=[CH2:37])[CH2:32][CH2:33][CH2:34][CH2:35]3)[C@@H:21]2[OH:30])[CH2:13]1

참가 물질

3

반응물 2

HCID 7841Allyl bromideHCID 228685452beta-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-16beta-(1-pyrrolidinyl)-5alpha-androstane-3alpha,17beta-diol

생성물 1

HCID 67684035HCID 67684035, 화합물수율 82%

실험 절차

2β-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol is reacted with allyl bromide as described in Example 5 to obtain the title compound in a yield of 82%, m.p.: 238°-240° C.

출처 및 근거

ORD 기록
ord-f08f0ff41dae412ea28d0eb683bd7670
출처 데이터셋
uspto-grants-1997_01
특허 번호
US05591735

연결된 노트

불러오는 중…