반응식
[CH2:1]([SH:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+].[Cl:10][C:11]1[CH:20]=[C:19]2[C:14]([CH:15]=[CH:16][C:17]([CH2:21][O:22][C:23]3[CH:38]=[CH:37][C:26]4[O:27][CH2:28][C:29]5[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=5[C:31](=[O:32])[C:25]=4[CH:24]=3)=[N:18]2)=[CH:13][C:12]=1F>CN(C)C=O>[Cl:10][C:11]1[CH:20]=[C:19]2[C:14]([CH:15]=[CH:16][C:17]([CH2:21][O:22][C:23]3[CH:38]=[CH:37][C:26]4[O:27][CH2:28][C:29]5[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=5[C:31](=[O:32])[C:25]=4[CH:24]=3)=[N:18]2)=[CH:13][C:12]=1[S:3][CH2:1][CH3:2]참가 물질
5
반응 조건
- 온도
- 90 °C
실험 절차
0.37 ml of ethyl mercaptan and 1.12 g of potassium carbonate were added to 2.0 g of 2-(7-chloro-6-fluoroquinolin-2-yl)methoxy-11-oxo-6,11-dihydrodibenz[b,e]oxepine dissolved in 80 ml of dimethylformamide and the mixture was stirred at 90° C. for 4 hours.
출처 및 근거
- ORD 기록
- ord-173c904036b3494ca7a6e3278b1b792f
- 출처 데이터셋
- uspto-grants-1997_01
- 특허 번호
- US05591752
연결된 노트
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