Tetrahydrofuran → N-(3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyridin-2-yl)-1-chloro-6-methylisoquinolin-5-amine

HRID 2329526

반응식

[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][Si:31]([N-:32][Si:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:17][c:18]1[n:19][cH:20][cH:21][c:22]2[c:23]([NH2:29])[c:24]([CH3:28])[cH:25][cH:26][c:27]12.[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][cH:15][cH:16]2.[Li+:39]>>[c:2]1([NH:29][c:23]2[c:22]3[cH:21][cH:20][n:19][c:18]([Cl:17])[c:27]3[cH:26][cH:25][c:24]2[CH3:28])[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][cH:15][cH:16]2