Formic Acid → 3-(Formylamino)benzoic acid

HRID 2332

반응식

HRID 2332 반응식
[C:1](OC(=O)C)(=[O:3])C.C(O)=O.[NH2:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16]>O>[CH:1]([NH:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16])=[O:3]

참가 물질

5

반응물 3

HCID 284Formic AcidHCID 74193-Aminobenzoic AcidHCID 7918Acetic Anhydride

생성물 1

HCID 152489873-(Formylamino)benzoic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Acetic anhydride (76 ml) was added to 98% formic acid (130 ml) and the mixture stirred at r.t. 30 min, then 3-aminobenzoic acid (15 g, 109.5 mmol) added. The mixture was stirred at r.t. for 1 h, then water (1.3 L) added and stirring continued overnight. The resultant white precipitate was collected, washed with water and dried in vacuo over P2O5 (15.4 g, 85%).

후처리

  1. stirringThe mixture was stirred at r.t. for 1 h
  2. stirringstirring continued overnight
  3. customThe resultant white precipitate was collected
  4. washwashed with water
  5. dry with materialdried in vacuo over P2O5 (15.4 g, 85%)

출처 및 근거

ORD 기록
ord-5570e335404a45e8bde112385306c6b2
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05728829

연결된 노트

불러오는 중…