Chloride → ethyl (2RS,3RS)-3-(4-fluorophenyl)-2-((3-fluoro-4-(trifluoromethyl)phenyl)methyl)-3-hydroxypropionate

반응식

[BH4-:1].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[Cl-:36].[Cl-:38].[ClH:30].[F:3][c:4]1[cH:5][cH:6][c:7]([C:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[cH:19][c:20]([F:28])[c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)=[O:29])[cH:8][cH:9]1.[Na+:2].[Zn+2:37]>>[F:3][c:4]1[cH:5][cH:6][c:7]([CH:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[cH:19][c:20]([F:28])[c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)[OH:29])[cH:8][cH:9]1