Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Isopropylphenylboronic acid → N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Isopropylphenylboronic acid | HCID 2773480 | — |
| 반응물 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 생성물 | N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole | HCID 22998466 | 84% |
반응 단계
N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 33C, from 4-isopropylphenyl boronic acid and N-(5-bromothiophene sulfonyl)-pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as an off white colored solid in 84% yield, m.p. 112°-114° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05594021 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-751e1ce0333f4b6d9945f5e2e9fcd00e |
| 출처 메모 | uspto-grants-1997_01 |