Chlorosulfonic acid → 2-Ethylbenzo[b]furan-3-sulfonyl chloride
반응식
[CH2:1]([C:3]1[O:7][C:6]2[CH:8]=[CH:9][CH:10]=[CH:11][C:5]=2[CH:4]=1)[CH3:2].[Cl:12][S:13](O)(=[O:15])=[O:14].P(Cl)(Cl)(Cl)(Cl)Cl>C(Cl)Cl>[CH2:1]([C:3]1[O:7][C:6]2[CH:8]=[CH:9][CH:10]=[CH:11][C:5]=2[C:4]=1[S:13]([Cl:12])(=[O:15])=[O:14])[CH3:2]참가 물질
5
실험 절차
2-Ethylbenzo[b]furan-3-sulfonyl chloride was prepared by the method of Example 82C with 2-ethylbenzo[b]furan (6.9 mmols, 1.0 g), chlorosulfonic acid (8.9 mmols, 0.6 ml) phosphorous oxychloride (21 mmols, 1.9 ml), phosphorous pentachloride (6.9 mmols, 1.4 g) and CH2Cl2 (10 ml). Flash chromatography (2% ethyl acetate/hexanes) provided 0.71 g (42%) of an orange solid.
출처 및 근거
- ORD 기록
- ord-6bbbd6bb37f840c49a7453d254ec080f
- 출처 데이터셋
- uspto-grants-1997_01
- 특허 번호
- US05594021
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