Tetrahydrofuran → (9-(2-Fluoro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone

반응식

[C:19]([Si:20]([CH3:21])([CH3:22])[O:24][CH2:25][CH2:26][c:27]1[c:28]([F:55])[c:29]([CH2:30][N:31]2[CH2:32][CH2:33][C:34]3([CH2:35][N:36]([C:40](=[O:41])[c:42]4[n:43][c:44]([CH:47]([CH3:48])[CH3:49])[s:45][cH:46]4)[CH2:37][CH2:38][O:39]3)[CH2:50][CH2:51]2)[cH:52][cH:53][cH:54]1)([CH3:23])([CH3:56])[CH3:57].[CH2:2]([N+:3]([CH2:4][CH2:5][CH2:6][CH3:7])([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:12][CH2:13][CH2:14][CH3:15])[CH2:16][CH2:17][CH3:18].[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[F-:1]>>[OH:24][CH2:25][CH2:26][c:27]1[c:28]([F:55])[c:29]([CH2:30][N:31]2[CH2:32][CH2:33][C:34]3([CH2:35][N:36]([C:40](=[O:41])[c:42]4[n:43][c:44]([CH:47]([CH3:48])[CH3:49])[s:45][cH:46]4)[CH2:37][CH2:38][O:39]3)[CH2:50][CH2:51]2)[cH:52][cH:53][cH:54]1