Phosphoric Acid → HCID 23649026, 화합물

HRID 2354543노트

반응식

HRID 2354543 반응식
[OH:1][P:2]([OH:5])([OH:4])=[O:3].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O.[NH2:20][C:21]1([CH2:40]O)[CH2:25][CH2:24][CH:23]([C:26]2[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])=[CH:28][CH:27]=2)[CH2:22]1>O>[P:2]([OH:5])([OH:4])([O:1][CH2:40][C:21]1([NH2:20])[CH2:25][CH2:24][CH:23]([C:26]2[CH:27]=[CH:28][C:29]([CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])=[CH:30][CH:31]=2)[CH2:22]1)=[O:3]

참가 물질

5

반응물 3

HCID 1004Phosphoric AcidHCID 14812Phosphorus oxide (P4O10)2회HCID 11623636HCID 11623636, 화합물

생성물 1

HCID 23649026HCID 23649026, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
100 °C

실험 절차

1 mL 85% H3PO4 was slowly drop added into 0.5 g of P2O5, the acid-anhydride mixture was then heated at 100° C. for 1 hour under nitrogen protection. Another 0.5 g of P2O5 and 30 mg of 6 were added to the poly phosphoric acid and heated for 5 hours at 100° C. After cooling down to RT, 10 mL icy cold water was added to reaction mixture. Product precipitated out as white solid. The product was collected and washed with water. 31 mg (82%) green colored product was collected after vacuum dry. MS only two peaks: M+1=384.4 with 304.4 (hydrolyzed back to 6).

후처리

  1. temperatureAfter cooling down to RT
  2. customProduct precipitated out as white solid
  3. customThe product was collected
  4. washwashed with water
  5. custom31 mg (82%) green colored product was collected after vacuum
  6. customdry

출처 및 근거

ORD 기록
ord-50b5fcedf26e40528de6d2aa5e6dad32
출처 데이터셋
uspto-grants-2010_07
특허 번호
US07754703B2

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