Pyruvic Acid → 2-[2-(4-Chlorophenyl)hydrazinylidene]propanoic acid

HRID 235616

반응식

HRID 235616 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[C:10]([OH:15])(=[O:14])[C:11]([CH3:13])=O>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][N:9]=[C:11]([CH3:13])[C:10]([OH:15])=[O:14])=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 1060Pyruvic AcidHCID 70624(4-Chlorophenyl)hydrazine

생성물 1

HCID 2284632-[2-(4-Chlorophenyl)hydrazinylidene]propanoic acid

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
70 °C

실험 절차

75.7 g of hydrochloric salt of parachlorophenylhydrazine was dissolved into 350 ml of water. 37.2 g of pyruvic acid was added into the solution. After stirring for 30 minutes at 70° C. while heating, and then cooling, precipitated crystals were filtered out, washed, and dried. These crystals were recrystallized from isopropyl acohol to obtain 57 g of 2-(p-chlorophenylhydrazono)propionic acid having a melting point of 196° to 197° C. (decomposed).

후처리

  1. temperaturewhile heating
  2. temperaturecooling
  3. customprecipitated crystals
  4. filtrationwere filtered out
  5. washwashed
  6. customdried
  7. customThese crystals were recrystallized from isopropyl acohol

출처 및 근거

ORD 기록
ord-e983d2b21ed74c50872c53dbc60acdb2
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04640892

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