반응식
C(O)(=O)C1C=CC=CC=1.S(=O)(=O)(O)O.S(=O)(=O)=O.[S:19]([C:23]1[CH:24]=[C:25]([CH:29]=[CH:30][CH:31]=1)[C:26]([OH:28])=[O:27])([OH:22])(=[O:21])=[O:20].[N+:32]([O-])([OH:34])=[O:33]>>[N+:32]([C:30]1[CH:29]=[C:25]([CH:24]=[C:23]([S:19]([OH:22])(=[O:21])=[O:20])[CH:31]=1)[C:26]([OH:28])=[O:27])([O-:34])=[O:33]참가 물질
6
실험 절차
Benzoic acid was sulfonated by heating it with concentrated sulfuric acid in the presence of sulfur trioxide. The 3-sulfobenzoic acid was nitrated with fuming nitric acid to yield 3-nitro-5-sulfobenzoic acid. Hydrogenation of this in 50% ethanol/water over palladium on charcoal easily afforded 3-amino-5-sulfobenzoic acid in good yield. Structural verification was obtained by carbon magnetic resonance, proton magnetic resonance and infra-red analysis.
출처 및 근거
- ORD 기록
- ord-747374bb87c74b8c8c7bfdc4ca2aba2a
- 출처 데이터셋
- uspto-grants-1987_02
- 특허 번호
- US04642240
연결된 노트
불러오는 중…