Stannous Chloride → 3-(2-Amino-4-chloro-phenoxy)-N,N-dimethyl-benzamide

HRID 2358743노트

반응식

HRID 2358743 반응식
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=2)[C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[C:4]([N+:20]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:20][C:4]1[CH:3]=[C:2]([Cl:1])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=1)[C:10]([N:12]([CH3:13])[CH3:14])=[O:11]

참가 물질

3

반응물 2

HCID 24479Stannous ChlorideHCID 684583013-(4-Chloro-2-nitro-phenoxy)-N,N-dimethyl-benzamide

생성물 1

HCID 684592683-(2-Amino-4-chloro-phenoxy)-N,N-dimethyl-benzamide수율 68%

실험 절차

The product from Example 168c (1.5 g, 4.6 mmol) was reacted with SnCl2 as described in Example 1f to give the title compound (0.91 g, 68%).

출처 및 근거

ORD 기록
ord-9712546d3da34aa6aaaf9fc167193eb0
출처 데이터셋
uspto-grants-2010_07
특허 번호
US07763731B2

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