Dimethylformamide dimethyl acetal → HCID 67260579, 화합물

HRID 2359062

반응식

HRID 2359062 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([C:7](=[O:9])[CH3:8])[S:5][CH:6]=1.CO[CH:12](OC)[N:13]([CH3:15])[CH3:14]>>[CH3:12][N:13]([CH3:15])[CH:14]=[CH:8][C:7]([C:4]1[S:5][CH:6]=[C:2]([CH3:1])[CH:3]=1)=[O:9]

참가 물질

3

반응물 2

HCID 78373Dimethylformamide dimethyl acetalHCID 836541-(4-Methyl-2-thienyl)ethan-1-one

생성물 1

HCID 67260579HCID 67260579, 화합물수율 100%

실험 절차

A mixture of 1-(4-methyl-2-thienyl)ethanone (70.8 mmol) and N,N-dimethylformamide dimethyl acetal (105.1 mmol) was refluxed overnight and then allowed to cool to room temperature. The reaction mixture was concentrated under reduced pressure and dried in vacuo to afford 13.8 g (100% yield) of 3-(dimethylamino)-1-(4-methyl-2-thienyl)prop-2-en-1-one which was used in the next step without further purification.

후처리

  1. temperaturewas refluxed overnight
  2. concentrationThe reaction mixture was concentrated under reduced pressure
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-5059afaa48714899a0071ff605fd7a13
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08685974B2

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