Hydrochloric Acid → HCID 53791715, 화합물

HRID 236295노트

반응식

HRID 236295 반응식
[NH2:1][C:2]1[N:7]([CH:8]2[CH2:11][CH2:10][CH2:9]2)[C:6](=[O:12])[NH:5][C:4](=[O:13])[CH:3]=1.Cl.[N:15]([O-])=[O:16].[Na+]>O>[NH2:1][C:2]1[N:7]([CH:8]2[CH2:9][CH2:10][CH2:11]2)[C:6](=[O:12])[NH:5][C:4](=[O:13])[C:3]=1[N:15]=[O:16]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 23668193Sodium NitriteHCID 538833266-Amino-1-cyclobutyl-2,4(1H,3H)-pyrimidinedione

생성물 1

HCID 53791715HCID 53791715, 화합물

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

3 g (0.0166 mol) of 6-amino-1-cyclobutyl-2,4-(1H,3H)-pyrimidinedione (VIII), was suspended in 25 ml water. To this was added 4 ml of 5N HCl and 1.3 g of NaNO2 (0.019 mol) which was dissolved in water. The reaction mixture was stirred for 3 hours and the red crystals were filtered off and washed with water. Yield 3.1 g (89%) (IX) NMR.

후처리

  1. filtrationthe red crystals were filtered off
  2. washwashed with water

출처 및 근거

ORD 기록
ord-3a953e0f18284e1491beeaf53ad39c44
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04644001

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