Benzaldehyde → N-[2-(diphenylphosphino)ethyl]-N-[phenylmethylene]amine

HRID 2364112

반응식

HRID 2364112 반응식
[C:1]1([P:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][CH2:9][NH2:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:17](=O)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(O)C>[C:1]1([P:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][CH2:9][N:10]=[CH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 240BenzaldehydeHCID 273264(2-Aminoethyl)diphenylphosphine

생성물 1

HCID 12145947N-[2-(diphenylphosphino)ethyl]-N-[phenylmethylene]amine수율 98%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Under argon, a solution of 2-diphenylphosphino-ethylamine (590.3 mg, 2.57 mmol) and benzaldehyde (275.0 mg, 2.59 mmol) in ethanol (15 mL) was heated at 65° C. (oil bath) for 4 h. Then, the solvent was removed in-vacuo to give the desired product (>98% by 1H-NMR) as a colourless oil which solidified on standing (733.9 mg, 2.31 mmol, 90%).

후처리

  1. customThen, the solvent was removed in-vacuo

출처 및 근거

ORD 기록
ord-bce3ded93bba4133909b30d08d25708c
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08692022B2

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